Tetracyclines, Nursing Diagnosis, and Collaborative Problems - Pharmacology

Patients who receive tetracycline may also experience nephrogenicdiabetes insipidus, hepatotoxicity, pancreatitis, dizziness, syncope, and their skin might be increasingly sensitive to sunlight.

Here are the common nursing diagnoses that are the related to a patient who is receiving tetracyclines.

  • Altered comfort (heartburn and abdominal cramping)
  • Fluid volume deficit related to anorexia, nausea, and vomiting
  • Altered bowel elimination (diarrhea)
  • Altered protection related to loss of normal florae (fungal overgrowth)



Chloramphenicol is a broad-spectrum antibiotic that slows the growth of a wide variety of gram-positive and gram-negative bacteria. In high doses, chloramphenicol can kill bacteria. Chloramphenicol is given for treatment of meningitis (H influenzae, S pneumoniae, and N meningitides), parathyroid fever, Q fever, Rocky Mountain spotted fever, typhoid fever, typhus infections, brain abscesses, and bacterial septicemia.

Chloramphenicol should not be used for a patient who is pregnant or is breastfeeding. Neonates may develop gray syndrome, which is blue-gray skin, hypothermia, irregular breathing, coma, and cardiovascular collapse.

Chloramphenicol is not recommended for use with a patient who is under going radiation therapy or who has bone marrow depression.

Monitor the chloramphenicol serum level to assure that chloramphenicol stays within therapeutic limits. Chloramphenicol does have a seriously toxic effect on bone marrow. Patients have infrequently reported experiencing diarrhea, nausea, or vomiting. Serious adverse effects include blood dyscrasias, optic neuritis, and possibly irreversible bone marrow depression that may lead to aplastic anemia.

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